1,3-Propanediamine, N1,N1,N3-trimethyl- → 4-(3,5-Dichloropyridin-4-ylamino)-8-(5-((3-(dimethylamino)propyl)(methyl)amino)pentyloxy)-7-methoxy-2H-chromen-2-one

참여 물질

반응 단계

The title compound was prepared from N1,N1,N3-trimethylpropane-1,3-diamine and 8-(5-bromopentyloxy)-4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2H-chromen-2-one (Example 28) following the procedure outlined in Example 52. 1H NMR (400 MHz, DMSO-d6): δ 8.53 (s, 2H), 7.84 (d, 1H), 7.03 (d, 1H), 4.17 (br s, 1H), 3.96 (t, 2H), 3.87 (s, 3H), 2.54 (t, 4H), 2.45 (t, 2H), 2.31 (s, 3H), 2.27 (s, 6H), 1.69 (m, 2H), 1.64 (m, 2H), 1.56 (m, 2H), 1.47 (m, 2H); MS (ESI): 537.1.

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