Phosgene → HCID 53997918, 화합물
반응식
[NH2:1][C:2]1[S:3][C:4]([I:7])=[CH:5][N:6]=1.[C:8](Cl)(Cl)=[O:9]>C(OCC)(=O)C>[I:7][C:4]1[S:3][C:2]([N:1]=[C:8]=[O:9])=[N:6][CH:5]=1참가 물질
4
실험 절차
2-Amino-5-iodothiazole (19.0 grams) and a saturated solution of phosgene in ethyl acetate (200 ml) are charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. The reaction mixture is heated at reflux with stirring for a period of about 3 hours. After this time the reaction mixture is cooled and filtered to recover the desired product 5-iodothiazol-2-ylisocyanate dimer.
후처리
- customequipped with a mechanical stirrer
- temperaturethermometer and reflux condenser
- temperatureThe reaction mixture is heated
- temperatureat reflux
- temperatureAfter this time the reaction mixture is cooled
- filtrationfiltered
- customto recover the desired product 5-iodothiazol-2-ylisocyanate dimer
출처 및 근거
- ORD 기록
- ord-1bf52753ef7e4f2ab643f121c8ea9fbd
- 출처 데이터셋
- uspto-grants-1977_09
- 특허 번호
- US04046768
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