Acetone → HCID 18594874, 화합물

HRID 2071341노트

반응식

HRID 2071341 반응식
CS(O[CH:6]([CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH2:7][CH2:8][C@@H:9]1[C@@H:13]([CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][C:20]([O:22][CH2:23][CH3:24])=[O:21])[C:12](=[O:25])[CH2:11][CH2:10]1)(=O)=O.[CH3:31][C:32](C)=[O:33].[S:35]1C=CC=C1CC([O-])=O.[K+]>O>[C:32]([S:35][CH:6]([CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH2:7][CH2:8][C@@H:9]1[C@@H:13]([CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][C:20]([O:22][CH2:23][CH3:24])=[O:21])[C:12](=[O:25])[CH2:11][CH2:10]1)(=[O:33])[CH3:31]

참가 물질

5

반응물 3

HCID 180AcetoneHCID 18594876HCID 18594876, 화합물HCID 23696799Potassium 2-thienylacetate

생성물 1

HCID 18594874HCID 18594874, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A solution of 1 g. of ethyl 15-methanesulfonyloxy-9-oxo-prostanoate (Example 90) in 50 ml. of acetone containing 735 mg. of purified potassium thiolacetate is kept at the reflux temperature for 2 hours, then at room temperature for 18 hours. The mixture is diluted with water and the resulting solution is washed with saturated sodium chloride solution, dried with magnesium sulfate and taken to dryness. The residue is chromatographed on silica gel to give an oil;

후처리

  1. washthe resulting solution is washed with saturated sodium chloride solution
  2. dry with materialdried with magnesium sulfate
  3. customThe residue is chromatographed on silica gel
  4. customto give an oil

출처 및 근거

ORD 기록
ord-c41a485697ea4b60ad637c5013ee47c0
출처 데이터셋
uspto-grants-1977_09
특허 번호
US04046787

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