Thionyl Chloride → 4-(3-Amino-3-oxoprop-1-en-2-yl)benzoyl chloride

HRID 2071487노트

반응식

HRID 2071487 반응식
S(Cl)([Cl:3])=O.[C:5]([C:8]1[CH:18]=[CH:17][C:11]([C:12](=[CH2:16])[C:13]([NH2:15])=[O:14])=[CH:10][CH:9]=1)(O)=[O:6]>>[Cl:3][C:5]([C:8]1[CH:18]=[CH:17][C:11]([C:12](=[CH2:16])[C:13]([NH2:15])=[O:14])=[CH:10][CH:9]=1)=[O:6]

참가 물질

3

반응물 2

HCID 24386Thionyl ChlorideHCID 21413842HCID 21413842, 화합물

생성물 1

HCID 214138224-(3-Amino-3-oxoprop-1-en-2-yl)benzoyl chloride

실험 절차

A mixture of 50 cc. of thionyl chloride and 0.05 moles of p-carboxyatropamide is heated at reflux on the steam-bath for 1/2 hour. The reaction is concentrated in vacuo to give p-chlorocarbonylatropamide suitable for use in the following step.

후처리

  1. additionA mixture of 50 cc
  2. temperatureat reflux on the steam-bath for 1/2 hour
  3. concentrationThe reaction is concentrated in vacuo

출처 및 근거

ORD 기록
ord-635a9c89601e45ea8e8758710b9a9f56
출처 데이터셋
uspto-grants-1977_09
특허 번호
US04046905

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