Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → Biphenyl-4-carboxylic acid 2-methylbutyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 1,1-Dibromododecane | HCID 11324906 | — |
| 반응물 | 4-Hydroxybiphenyl-4-carboxylic acid 2-methylbutyl ester | HCID 67860692 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | Biphenyl-4-carboxylic acid 2-methylbutyl ester | HCID 19887231 | 65% |
반응 단계
63 mmols (18 g) of the ester 1a obtained in Examples 1 and 2, 0.12 mol (39.4 g) of dibromododecane and 0.25 mol (34.6 g) of potassium carbonate were refluxed in 600 ml of acetone for 8 hours. The reaction mixture was filtered and the filtrate was concentrated, purified by column chromatography and recrystallized from ethanol to obtain 21.8 g (yield 65%) of 4'-12-bromodoecyloxy) biphenyl-4-carboxylic acid 2-methylbutyl ester {monobromo compound 1d, [α]23D=+2.85 (chloroform)}.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04915867 |
| 출처 데이터셋 | uspto-grants-1990_04 |
| ORD ID | ord-d35ffcf150c04635be09338706bf13e3 |
| 출처 메모 | uspto-grants-1990_04 |