Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide → 1-[(3-Methylbutoxy)methyl]-3-nitrobenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | alpha-Chloro-m-nitrotoluene | HCID 12078 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | Isoamyl Alcohol | HCID 31260 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 1-[(3-Methylbutoxy)methyl]-3-nitrobenzene | HCID 14330147 | — |
반응 단계
Into a mixture of 500 ml (4.59 mol) of 3-methyl-1-butanol and 140 ml of dimethylformamide, 158.1 g (0.92 mol) of 3-chloromethylnitrobenzene was dissolved, and 78 g (1.39 mol) of potassium hydroxide pellets was added to the thus formed solution while cooling with water under a vigorous stirring. The temperature of the reaction mixture rised to 43° C. and then dropped slowly to room temperature. Thereafter, the reaction mixture was stirred for 7 hours at room temperature to complete the reaction.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04919707 |
| 출처 데이터셋 | uspto-grants-1990_04 |
| ORD ID | ord-f1b386a450db4221819a68079da793cd |
| 출처 메모 | uspto-grants-1990_04 |