Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 2-Amino-3-(2-methyl-6-methoxycarbonylaminobenzylamino)pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 반응물 | 2-Amino-3-(2-methyl-6-methoxycarbonylaminobenzylideneamino)pyridine | HCID 14499824 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 2-Amino-3-(2-methyl-6-methoxycarbonylaminobenzylamino)pyridine | HCID 14499817 | 94.1% |
반응 단계
To a solution of 2-amino-3-(2-methyl-6-methoxycarbonylaminobenzylideneamino)pyridine (229 mg) in methanol (4.6 ml) and chloroform (4.6 ml) was added sodium borohydride (200 mg) and the mixture was stirred for 3.5 hours at room temperature. After water was added, organic layer was separated and dried over magnesium chloride. The solvent was evaporated under reduced pressure. The residue was triturated with diethyl ether to give 2-amino-3-(2-methyl-6-methoxycarbonylaminobenzylamino)pyridine (217 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04920129 |
| 출처 데이터셋 | uspto-grants-1990_04 |
| ORD ID | ord-7b8224e273b24a24b6518a7792f389bf |
| 출처 메모 | uspto-grants-1990_04 |