Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Oxalyl chloride → 2,3,4,5-Tetrafluoro-6-methylbenzoyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Oxalyl chloride | HCID 65578 | — |
| 반응물 | 2,3,4,5-Tetrafluoro-6-methylbenzoic acid | HCID 12943997 | — |
| 촉매 | Dimethylformamide | HCID 6228 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2,3,4,5-Tetrafluoro-6-methylbenzoyl chloride | HCID 14651256 | 98.6% |
반응 단계
A solution of 8.2 g (39.4 mmol) of 2,3,4,5-tetrafluoro-6-methylbenzoic acid, 6.0 g (47.2 mmol) of oxalyl chloride, and 100 ml of dichloromethane was treated with three drops of DMF. The solution was stirred for three hours, then concentrated to give 8.8 g of the title compound as a yellow liquid. The product was used as is in the next step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04920120 |
| 출처 데이터셋 | uspto-grants-1990_04 |
| ORD ID | ord-6ecd8f605e7e43df9c43fd84ea9c59fb |
| 출처 메모 | uspto-grants-1990_04 |