Dimethylformamide → HCID 15075815, 화합물
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[F:1][C:2]1[C:7]([Si](C)(C)C)=[C:6]([F:12])[C:5]([F:13])=[C:4]([CH3:14])[C:3]=1[C:15]1[O:16][CH2:17][C:18]([CH3:21])([CH3:20])[N:19]=1.[F-].[Cs+].CN(C)C=O>O>[F:1][C:2]1[CH:7]=[C:6]([F:12])[C:5]([F:13])=[C:4]([CH3:14])[C:3]=1[C:15]1[O:16][CH2:17][C:18]([CH3:21])([CH3:20])[N:19]=1참가 물질
5
실험 절차
A solution of 12.0 g (38.0 mmol) of 2-[2,4,5-trifluoro-6-methyl-3-(trimethylsilyl)phenyl]-4,4-dimethyl-2-oxazoline, 5.85 g (38.5 mmol) of cesium fluoride, 110 ml of dimethylformamide, and 15 ml of water was stirred for 18 hours at room temperature. The reaction mixture was poured into water and extracted with ethyl acetate; the organic phase was washed with water, dried over magnesium sulfate, and concentrated to give 9.1 g of liquid.
후처리
- extractionextracted with ethyl acetate
- washthe organic phase was washed with water
- dry with materialdried over magnesium sulfate
- concentrationconcentrated
출처 및 근거
- ORD 기록
- ord-ce26c97b41c945258ac376128b9e370c
- 출처 데이터셋
- uspto-grants-1990_04
- 특허 번호
- US04920120
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