HCID 67096291, 화합물 → [3-Methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-[8-(3-methoxy-phenyl)-8-propyl-5,6,7,8-tetrahydro-quinazolin-2-yl]-amine
반응식
CN(C)[CH:3]=[C:4]1[C:9](=O)[C:8]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([O:20][CH3:21])[CH:15]=2)([CH2:11][CH2:12][CH3:13])[CH2:7][CH2:6][CH2:5]1.[N+]([O-])(O)=O.[N+]([O-])(O)=O.[CH3:31][O:32][C:33]1[CH:34]=[C:35]([NH:45][C:46]([NH2:48])=[NH:47])[CH:36]=[CH:37][C:38]=1[N:39]1[CH:43]=[C:42]([CH3:44])[N:41]=[CH:40]1>>[CH3:31][O:32][C:33]1[CH:34]=[C:35]([NH:45][C:46]2[N:48]=[CH:3][C:4]3[CH2:5][CH2:6][CH2:7][C:8]([C:14]4[CH:19]=[CH:18][CH:17]=[C:16]([O:20][CH3:21])[CH:15]=4)([CH2:11][CH2:12][CH3:13])[C:9]=3[N:47]=2)[CH:36]=[CH:37][C:38]=1[N:39]1[CH:43]=[C:42]([CH3:44])[N:41]=[CH:40]1참가 물질
3
실험 절차
The title compound was prepared from 6-[1-dimethylamino-methylidene]-2-(3-methoxy-phenyl)-2-propyl-cyclohexanone (101 mg, 0.33 mmol) and N-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-guanidine dinitrate (124 mg, 0.33 mmol) using in analogous manner the procedure described in example 45b). Obtained as white solid (24 mg, 15%). MS ISP (m/e): 484.5 [(M+H)+]. mp 166-168° C.
출처 및 근거
- ORD 기록
- ord-dff8163687914af19bc4748f6849805d
- 출처 데이터셋
- uspto-grants-2011_04