3-Methoxyphenol → 4-Hydroxy-8-(3-methoxy-phenoxy)-isoquinoline-3-carboxylic acid methyl ester

HRID 2077161노트

반응식

HRID 2077161 반응식
[CH3:1][O:2][C:3]([C:5]1[N:6]=[CH:7][C:8]2[C:13]([C:14]=1[OH:15])=[CH:12][CH:11]=[CH:10][C:9]=2I)=[O:4].[CH3:17][O:18][C:19]1[CH:20]=[C:21]([OH:25])[CH:22]=[CH:23][CH:24]=1>>[CH3:1][O:2][C:3]([C:5]1[N:6]=[CH:7][C:8]2[C:13]([C:14]=1[OH:15])=[CH:12][CH:11]=[CH:10][C:9]=2[O:25][C:21]1[CH:22]=[CH:23][CH:24]=[C:19]([O:18][CH3:17])[CH:20]=1)=[O:4]

참가 물질

3

반응물 2

HCID 90073-MethoxyphenolHCID 67110147Methyl 4-hydroxy-8-iodoisoquinoline-3-carboxylate

생성물 1

HCID 671103644-Hydroxy-8-(3-methoxy-phenoxy)-isoquinoline-3-carboxylic acid methyl ester

실험 절차

The title compound was synthesized from 4-hydroxy-8-iodo-isoquinoline-3-carboxylic acid methyl ester and 3-methoxy-phenol in analogy to example 19d; MS-(+)-ion: M+1=326.4.

출처 및 근거

ORD 기록
ord-7cd2df6c90244973a47fef18f7746925
출처 데이터셋
uspto-grants-2011_04
특허 번호
US07928120B2

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