HCID 23146349, 화합물 → HCID 23146332, 화합물

반응식

[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([CH2:10][CH:11]3[CH2:16][N:15](C)[CH2:14][CH2:13][N:12]3[C:18]([C:20]3[N:21]=[C:22]([CH3:32])[S:23][C:24]=3[C:25]3[CH:30]=[CH:29][C:28]([F:31])=[CH:27][CH:26]=3)=[O:19])=[CH:7][C:6]=2[CH:33]=1.C1C=C2C(N/N=C3/C4C=CC(S([O-])(=O)=O)=CC=4C=C(S([O-])(=O)=O)C/3=O)=CC=C(S([O-])(=O)=O)C2=CC=1.[Na+].[Na+].[Na+]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([CH2:10][CH:11]3[CH2:16][NH:15][CH2:14][CH2:13][N:12]3[C:18]([C:20]3[N:21]=[C:22]([CH3:32])[S:23][C:24]=3[C:25]3[CH:30]=[CH:29][C:28]([F:31])=[CH:27][CH:26]=3)=[O:19])=[CH:7][C:6]=2[CH:33]=1

참가 물질

반응물 2

HCID 23146349HCID 23146349, 화합물

HCID 178516958HCID 178516958, 화합물

생성물 1

HCID 23146332HCID 23146332, 화합물

실험 절차

The title compound was prepared from 1-[2-(5-chloro-benzofuran-2-ylmethyl)-4-methyl-piperazin-1-yl]-1-[5-(4-fluoro-phenyl)-2-methyl-thiazol-4-yl]-methanone, E123 (95 mg) by a procedure similar to that described for Example 85.

출처 및 근거

ORD 기록: ord-1f6f80c13dec487e8aea44e30672fb9e
출처 데이터셋: uspto-grants-2011_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07928124B2

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