1,2-dimethyl-1H-imidazole-4-sulfonamide → 2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl-(1,2-dimethyl-1H-imidazol-4-yl)sulfonylcarbamate
반응식
[C:1](=[O:34])(OC1C=CC=CC=1)[O:2][CH2:3][CH2:4][C:5]1[CH:10]=[CH:9][C:8]([N:11]2[C:15]3[CH:16]=[C:17]([Cl:24])[C:18]([C:20]([F:23])([F:22])[F:21])=[CH:19][C:14]=3[N:13]=[C:12]2[CH2:25][CH3:26])=[CH:7][CH:6]=1.[CH3:35][N:36]1[CH:40]=[C:39]([S:41]([NH2:44])(=[O:43])=[O:42])[N:38]=[C:37]1[CH3:45]>>[Cl:24][C:17]1[C:18]([C:20]([F:21])([F:22])[F:23])=[CH:19][C:14]2[N:13]=[C:12]([CH2:25][CH3:26])[N:11]([C:8]3[CH:9]=[CH:10][C:5]([CH2:4][CH2:3][O:2][C:1](=[O:34])[NH:44][S:41]([C:39]4[N:38]=[C:37]([CH3:45])[N:36]([CH3:35])[CH:40]=4)(=[O:42])=[O:43])=[CH:6][CH:7]=3)[C:15]=2[CH:16]=1참가 물질
3
반응물 2
생성물 1
실험 절차
The title compound was prepared according to the procedure described in step 2 of Example 243 from 2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl phenyl carbonate and 1,2-dimethyl-1H-imidazol-4-ylsulfonamide.
출처 및 근거
- ORD 기록