Thionyl Chloride → 2-(3-Chlorophenyl)-2-methylpropanoyl chloride

반응식

[Cl:1][C:2]1[CH:3]=[C:4]([C:8]([CH3:13])([CH3:12])[C:9](O)=[O:10])[CH:5]=[CH:6][CH:7]=1.S(Cl)([Cl:16])=O>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]([CH3:13])([CH3:12])[C:9]([Cl:16])=[O:10])[CH:5]=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 24386Thionyl Chloride

HCID 155826442-(3-Chlorophenyl)-2-methylpropanoic acid

생성물 1

HCID 139875312-(3-Chlorophenyl)-2-methylpropanoyl chloride

실험 절차

2-(3-Chlorophenyl)-2-methylpropanoic acid (5.7 g, 28.7 mmol) was stirred in thionyl chloride (100 mL) for 2 hours at reflux. The thionyl chloride was removed under vacuum to give the product (5.69 g).

후처리

temperatureat reflux
customThe thionyl chloride was removed under vacuum

출처 및 근거

ORD 기록: ord-e875b7ed7d81462790be6475de18cdd0
출처 데이터셋: uspto-grants-2011_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07928139B2

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