Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetone → 2-Methyl-2-piperidin-1-ylpropanenitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetone | HCID 180 | — |
| 반응물 | Potassium Cyanide | HCID 9032 | — |
| 반응물 | Piperidine, hydrochloride (1:1) | HCID 2723721 | — |
| 반응물 | 1-(Dimethylamino)cyclopentanecarbonitrile | HCID 10773049 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2-Methyl-2-piperidin-1-ylpropanenitrile | HCID 288882 | 77% |
반응 단계
The title compound (2.33 g, 77%) was prepared from piperidine hydrochloride (2.43 g, 20 mmol), acetone (1.16 g, 20 mmol) and potassium cyanide (1.30 g, 20 mmol) in water (10 ml) in a similar manner to that described in D1. 1H NMR (CDCl3) δ: 1.46 (2H, m), 1.50 (6H, s), 1.63 (4H, m), 2.59 (4H, m).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07745642B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-512a6c3f8abe44da91d6031f77031de6 |
| 출처 메모 | uspto-grants-2010_06 |