Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cyclopentanone → 1-(1-Azetidinyl)cyclopentanecarbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cyclopentanone | HCID 8452 | — |
| 반응물 | Potassium Cyanide | HCID 9032 | — |
| 반응물 | 1-(Dimethylamino)cyclopentanecarbonitrile | HCID 10773049 | — |
| 반응물 | Azetidine hydrochloride | HCID 12308726 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 1-(1-Azetidinyl)cyclopentanecarbonitrile | HCID 59347779 | 43% |
반응 단계
The title compound (1.29 g, 43%) was prepared from azetidine hydrochloride (1.85 g, 20 mmol), cyclopentanone (1.68 g, 20 mmol) and potassium cyanide (1.30 g, 20 mmol) in water (10 ml) in a similar manner to that described in D1. 1H NMR (CDCl3) δ: 1.70-1.82 (6H, m), 1.86 (2H, m), 2.07 (2H, quin, J=7 Hz), 3.32 (4H, t, J=7 Hz).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07745642B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-c1121d5546834bab92e2bff97a8f4126 |
| 출처 메모 | uspto-grants-2010_06 |