Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Nitro-4-trifluoromethylanisole → 2-Methoxy-5-(trifluoromethyl)aniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Nitro-4-trifluoromethylanisole | HCID 96748 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 2-Methoxy-5-(trifluoromethyl)aniline | HCID 600637 | 99% |
반응 단계
A mixture of 4-methoxy-3-nitrobenzotrifluoride and 10% of 10% Pd/C in methanol was stirred under H2 atmosphere overnight at room temperature. The reaction mixture was filtered through celite, concentrated and dried under vacuum to provide product as an off white solid in 99% yield. ES/MS m/z 192.1 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07932262B2 |
| 출처 데이터셋 | uspto-grants-2011_04 |
| ORD ID | ord-0e11a43a96194bd6b45518dc8d910a74 |
| 출처 메모 | uspto-grants-2011_04 |