Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl ketone → 2-Ethyl-2-(1-pyrrolidinyl)butanenitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl ketone | HCID 7288 | — |
| 반응물 | Potassium Cyanide | HCID 9032 | — |
| 반응물 | Pyrrolidine | HCID 31268 | — |
| 반응물 | 2-Methyl-2-(pyrrolidin-1-yl)propanenitrile | HCID 12570647 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2-Ethyl-2-(1-pyrrolidinyl)butanenitrile | HCID 43802763 | 100% |
반응 단계
The title compound (8.8 g, 100%) was prepared from pyrrolidine (8.96 ml, 0.107 mol), 3-pentanone (8.61 g, 0.1 mol) and potassium cyanide (6.51 g, 0.1 mol) in water (50 ml) in a similar manner to that described in D4. 1H NMR (CDCl3) δ: 0.95 (6H, t, J=7.6 Hz), 1.67-1.90 (8H, m), 2.67-2.72 (4H, m).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07745642B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-75a495d4416547e6947399e69d4fc15d |
| 출처 메모 | uspto-grants-2010_06 |