Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Benzylfuran-2-carbaldehyde → 5-(Phenylmethyl)-2-furanmethanamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Benzylfuran-2-carbaldehyde | HCID 12418537 | — |
| 반응물 | Ammonia methanol | HCID 21705897 | — |
| 촉매 | Nickel | HCID 935 | — |
| 생성물 | 5-(Phenylmethyl)-2-furanmethanamine | HCID 23130620 | 65.8% |
반응 단계
7N Ammonia/methanol(40 mL) and Raney nickel(3 g) were added to 5-benzyl-furan-2-carbaldehyde described in Preparation Example 39 (2.5 g, 13 mmol), and the solution was stirred for 22 hours under hydrogen atmosphere at room temperature. After removing the catalyst by filtering through Celite pad, the solvent was evaporated in vacuo and C-(5-benzyl-furan-2-yl)methylamine (1.6 g, 8.6 mmol, 65.8%) was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07932272B2 |
| 출처 데이터셋 | uspto-grants-2011_04 |
| ORD ID | ord-fa9049e0f9524da9bf4ee48ab4ee6885 |
| 출처 메모 | uspto-grants-2011_04 |