Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrogen Cyanide → 1-[Methyl(phenylmethyl)amino]cyclopentanecarbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrogen Cyanide | HCID 768 | — |
| 반응물 | N-Methylbenzylamine | HCID 7669 | — |
| 반응물 | Cyclopentanone | HCID 8452 | — |
| 반응물 | Potassium Cyanide | HCID 9032 | — |
| 반응물 | 1-(Dimethylamino)cyclopentanecarbonitrile | HCID 10773049 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 1-[Methyl(phenylmethyl)amino]cyclopentanecarbonitrile | HCID 21581544 | 84% |
반응 단계
The title compound (15 g; 84%) was prepared from N-methylbenzylamine (10.08 g; 83 mmol), cyclopentanone (7 g; 83 mmol) and potassium cyanide (5.41 g; 83 mmol) in water (45 ml) in a similar manner to that described in D1. 1H NMR (CDCl3) δ: 1.90 (6H, m), 2.20 (3H, s), 2.3 (2H, m), 3.62 (2H, s), 7.25 (1H, m), 7.32 (4H, m); Mass Spectrum (Electrospray LC/MS): Found 188 (MH+−HCN). C14H18N2 requires 214. Ret. time 1.21 min.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07745642B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-3c8c8663029b447da3e44042b0133a60 |
| 출처 메모 | uspto-grants-2010_06 |