참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | N-(4-Chlorophenyl)-3-phenylacrylamide | HCID 303259 | — |
| 반응물 | Aluminum(III) Chloride | HCID 6451240 | — |
| 용매 | Chlorobenzene | HCID 7964 | — |
| 생성물 | 5-Chloroquinolin-2(1h)-one | HCID 12278036 | — |
반응 단계
To a mixture of N-(4-chlorophenyl)cinnamamide (8.3 g), and chlorobenzene (60 ml) was added portionwise aluminum chloride (21.4 g) under nitrogen at room temperature and the reaction mixture was slowly warmed up to 125° C. and kept at that temperature for 3 hours. The reaction mixture was cooled down and poured over 400 g of ice. The product crystallized out as a pink solid which was filtered and dried.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05728694 |
|---|
| 출처 데이터셋 | uspto-grants-1998_03 |
|---|
| ORD ID | ord-a8f8ef59267442b7ad02cb6e759c0c32 |
|---|
| 출처 메모 | uspto-grants-1998_03 |
|---|
