2-Fluoro-3-methoxyphenylboronic acid → 4-amino-7-fluoro-8-(2-fluoro-3-methoxyphenyl)-N-propyl-cinnoline-3-carboxamide
반응식
[F:20][c:21]1[c:22]([B:29]([OH:30])[OH:31])[cH:23][cH:24][cH:25][c:26]1[O:27][CH3:28].[NH2:1][c:2]1[c:3]([C:14](=[O:15])[NH:16][CH2:17][CH2:18][CH3:19])[n:4][n:5][c:6]2[c:7]([I:13])[c:8]([F:12])[cH:9][cH:10][c:11]12>>[NH2:1][c:2]1[c:3]([C:14](=[O:15])[NH:16][CH2:17][CH2:18][CH3:19])[n:4][n:5][c:6]2[c:7](-[c:22]3[c:21]([F:20])[c:26]([O:27][CH3:28])[cH:25][cH:24][cH:23]3)[c:8]([F:12])[cH:9][cH:10][c:11]12참가 물질
3
출처 및 근거
- ORD 기록
- ord-8120e95727c74c45a358d1af96287889
- 출처 데이터셋
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
반응 노트
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