4-(2-Thienyl)butanoic acid methyl ester → HCID 14952960, 화합물

HRID 2081878

반응식

HRID 2081878 반응식
N1C=CC(CC[C:9]([O:11]C)=[O:10])=CC=1.[S:13]1[CH:17]=[CH:16][CH:15]=[C:14]1[CH2:18][CH2:19][CH2:20][C:21]([O:23]C)=[O:22].[CH2:25]([C:29]1[N:30]([CH2:36][C:37]2[CH:42]=[CH:41][CH:40]=[CH:39][C:38]=2Cl)[C:31]([CH:34]=O)=[CH:32][N:33]=1)[CH2:26][CH2:27][CH3:28].CN1C(C=O)=CN=C1.C(C1N(CC2C=CC=CC=2Cl)C(/C=C(\CC2SC=CC=2)/C(O)=O)=CN=1)CCC>>[CH2:25]([C:29]1[N:30]([CH2:36][C:37]2[CH:42]=[CH:41][C:40]([C:9]([OH:11])=[O:10])=[CH:39][CH:38]=2)[C:31](/[CH:34]=[C:20](\[CH2:19][CH2:18][C:14]2[S:13][CH:17]=[CH:16][CH:15]=2)/[C:21]([OH:23])=[O:22])=[CH:32][N:33]=1)[CH2:26][CH2:27][CH3:28]

참가 물질

6

반응물 5

HCID 1407664-(2-Thienyl)butanoic acid methyl esterHCID 5735921-methyl-1H-imidazole-5-carbaldehydeHCID 3704115Methyl 3-(4-pyridyl)propanoateHCID 100474443-[2-Butyl-3-(2-chloro-benzyl)-3H-imidazol-4-yl]-2-thiophen-2-ylmethyl-acrylic acidHCID 101075301H-Imidazole-5-carboxaldehyde, 2-butyl-1-[(2-chlorophenyl)methyl]-

생성물 1

HCID 14952960HCID 14952960, 화합물

실험 절차

The title compound was prepared following the procedure of Example 20 replacing methyl 3-(4-pyridyl)propanoate with methyl 4-(2-thienyl)butanoate and 2-n-butyl-1-(2-chlorophenyl)methyl-1H-imidazol-5-carboxaldehyde with 2-n-butyl-1-)4-carbomethoxyphenyl)methyl-1H-imidazol-5-carboxaldehyde; mp 244°-246° C. (d).

출처 및 근거

ORD 기록
ord-be4cd52926ba466fbc598ef1afc1077c
출처 데이터셋
uspto-grants-1993_02
특허 번호
US05185351

연결된 노트

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