Sulfur Dioxide → HCID 67856346, 화합물

HRID 2081918노트

반응식

HRID 2081918 반응식
[CH2:1]([O:3][C:4]1[CH:11]=[CH:10][CH:9]=[CH:8][C:5]=1[CH2:6]Cl)[CH3:2].[Mg:12].[S:13](=[O:15])=[O:14]>C(OCC)C>[CH2:1]([O:3][C:4]1[CH:11]=[CH:10][CH:9]=[CH:8][C:5]=1[CH2:6][S:13]([O-:15])=[O:14])[CH3:2].[Mg+2:12].[CH2:1]([O:3][C:4]1[CH:11]=[CH:10][CH:9]=[CH:8][C:5]=1[CH2:6][S:13]([O-:15])=[O:14])[CH3:2]

참가 물질

5

반응물 3

HCID 1119Sulfur DioxideHCID 25302311-(Chloromethyl)-2-ethoxybenzeneHCID 5462224Magnesium

생성물 1

HCID 67856346HCID 67856346, 화합물

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

A Grignard solution of 30.5 of 2-ethoxybenzyl chloride and 6.1 g of magnesium shavings in 250 ml of diethyl ether is added dropwise at -60° C. to -70° C. to 50 ml of sulfur dioxide. Stirring is continued for 0.5 hour at -70° C., the mixture is allowed to come to room temperature, and the salt magnesium 2-ethoxybenzylsulfinate which has formed (47 g, melting point: 134°-139° C., decomposition) is filtered off with suction. The sulfinate salt is dissolved in 900 ml of water and 16.4 g of anhydrous sodium acetate. To this are added 22.7 g of hydroxylamine-O-sulfonic acid at room temperature with stirring. After the mixture has been stirred for 12 hours, the product is filtered off with suction and dried in vacuo. This give 23.9 g of 2-ethoxybenzylsulfonamide of melting point: 92°-93° C.

후처리

  1. customto come to room temperature

출처 및 근거

ORD 기록
ord-1c8530fb0a074f2681b680b11a1964c6
출처 데이터셋
uspto-grants-1993_02
특허 번호
US05186736

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