Methylamine → 1-[4-(Methylamino)piperidin-1-yl]ethan-1-one

HRID 2082351노트

반응식

HRID 2082351 반응식
[CH3:1][NH2:2].[C:3]([N:6]1[CH2:11][CH2:10][C:9](=O)[CH2:8][CH2:7]1)(=[O:5])[CH3:4]>C(O)C.[Pt]=O>[C:3]([N:6]1[CH2:11][CH2:10][CH:9]([NH:2][CH3:1])[CH2:8][CH2:7]1)(=[O:5])[CH3:4]

참가 물질

5

반응물 2

HCID 6329MethylamineHCID 122563N-Acetyl-4-piperidone

생성물 1

HCID 197612651-[4-(Methylamino)piperidin-1-yl]ethan-1-one

시약·촉매·용매 2

HCID 82844Platinum oxide (PtO)촉매HCID 702Ethanol용매2회

실험 절차

9.9 g of methylamine in 50 ml of ethanol are added to 14.4 g of 1-acetyl-4-oxopiperidine in 100 ml of ethanol. The mixture is then hydrogenated in the presence of platinum oxide at room temperature and atmospheric pressure, filtered and evaporated.

후처리

  1. filtrationatmospheric pressure, filtered
  2. customevaporated

출처 및 근거

ORD 기록
ord-d403338957fe41e2b26a0fbe34918afc
출처 데이터셋
uspto-grants-1993_02
특허 번호
US05189045

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