4-Hydroxybenzoic Acid → 4-(2-Bromoethoxy)-4'-hydroxybenzophenone

HRID 2082565

반응식

HRID 2082565 반응식
[O:1]([CH2:8][CH2:9][Br:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH:11][C:12]1[CH:20]=[CH:19][C:15]([C:16](O)=[O:17])=[CH:14][CH:13]=1>>[Br:10][CH2:9][CH2:8][O:1][C:2]1[CH:7]=[CH:6][C:5]([C:16]([C:15]2[CH:19]=[CH:20][C:12]([OH:11])=[CH:13][CH:14]=2)=[O:17])=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 1354-Hydroxybenzoic AcidHCID 68526Benzene, (2-bromoethoxy)-

생성물 1

HCID 127097874-(2-Bromoethoxy)-4'-hydroxybenzophenone

실험 절차

Melting points (mp) were obtained on a capillary melting point apparatus and are uncorrected. Elemental analyses of all compounds prepared were within ±0.4% of calculated theoretical values. Reaction progress and purity of products were checked by analytical TLC using 0.2 mm silica gel plastic backed layers, and viewed under light of 254 nm wavelength. Proton NMR spectra were obtained at 90 mHz and EIMS were obtained using a direct ion probe. 4-(2-Bromoethoxy)-4'-hydroxybenzophenone was prepared by acylation of 2-phenoxyethyl bromide with 4-hydroxybenzoic acid: mp 136°-138° C.

후처리

  1. customMelting points (mp) were obtained on a capillary
  2. customElemental analyses of all compounds prepared
  3. customReaction progress and purity of products
  4. customProton NMR spectra were obtained at 90 mHz
  5. customEIMS were obtained

출처 및 근거

ORD 기록
ord-55caa1af954947a0b9de6fd6d70f5be3
출처 데이터셋
uspto-grants-1993_02
특허 번호
US05189212

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