Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Iodohexane → N-n-Hexyl-N-(3-carbethoxy-5-ethyl-2-thienyl)-2-methylpropanamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Iodohexane | HCID 12527 | — |
| 반응물 | Ethyl 2-amino-5-ethyl-3-thenoate | HCID 78263 | — |
| 반응물 | Ethyl 5-ethyl-2-(2-methylpropanoylamino)thiophene-3-carboxylate | HCID 734585 | — |
| 생성물 | N-n-Hexyl-N-(3-carbethoxy-5-ethyl-2-thienyl)-2-methylpropanamide | HCID 53840912 | — |
반응 단계
Ethyl 2-amino-5-ethyl-3-thiophenecarboxylate (Chemische Berichte 99, 94 (1966) )was converted into N-(3-carbethoxy-5-ethyl-2-thienyl)-2-methylpropanamide by the method described in Example 41. Alkylation of the unpurified product with n-hexyl iodide as described in Example 43 gave the title compound as a light yellow oil, b.p. 145°-147° C/0.25 mm. NMR showed that the material was the correct product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04082771 |
| 출처 데이터셋 | uspto-grants-1978_04 |
| ORD ID | ord-6bf5cd6a7a2e41e497b0ff131b5cd5aa |
| 출처 메모 | uspto-grants-1978_04 |