1,3-Dibromopropane → HCID 20300304, 화합물

반응식

[Br:1][CH2:2][CH2:3][CH2:4]Br.[CH3:6][N:7]1[C:11](=[O:12])[C:10](=[O:13])[NH:9][C:8]1=[S:14]>>[Br:1][CH2:2][CH2:3][CH2:4][N:9]1[C:10](=[O:13])[C:11](=[O:12])[N:7]([CH3:6])[C:8]1=[S:14]

참가 물질

반응물 2

HCID 80011,3-Dibromopropane

HCID 203003261-Methyl-2-sulfanylideneimidazolidine-4,5-dione

생성물 1

HCID 20300304HCID 20300304, 화합물

실험 절차

By the procedure of Example 1(i), 1,3-dibromopropane was reacted with 1-methyl-2-thioxo-4,5-imidazolidinedione to yield 1-(3-bromopropyl)-3-methyl-2-thioxo-4,5-imidazolidinedione which, on reaction with thiourea by the procedure of Example 1(ii) gave S-[6-(1-(3-methyl-4,5-dioxo-2-thioxoimidazolidinyl))propyl]isothiourea hydrobromide. Hydrolysis of the latter compound by the procedure of Example 1(iii) and recrystallisation of the product from water gave the title compound, m.p. 141°-143°.

출처 및 근거

ORD 기록: ord-29d4085940964ae5b7f1b81f3c5837dc
출처 데이터셋: uspto-grants-1978_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04084001

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