Phosgene → 5,6-Dichlorobenzothiazol-2-yl isocyanate

HRID 2083647노트

반응식

HRID 2083647 반응식
[C:1](Cl)(Cl)=[O:2].[NH2:5][C:6]1[S:7][C:8]2[CH:14]=[C:13]([Cl:15])[C:12]([Cl:16])=[CH:11][C:9]=2[N:10]=1>C(OCC)(=O)C>[Cl:16][C:12]1[C:13]([Cl:15])=[CH:14][C:8]2[S:7][C:6]([N:5]=[C:1]=[O:2])=[N:10][C:9]=2[CH:11]=1

참가 물질

4

반응물 2

HCID 6371PhosgeneHCID 322065,6-Dichloro-2-benzothiazolamine

생성물 1

HCID 540279235,6-Dichlorobenzothiazol-2-yl isocyanate

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

A saturated solution of phosgene in ethyl acetate (200 ml) is charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. 2-Amino-5,6-dichlorobenzothiazole (0.1 mole) is added with stirring. After the addition is completed, the reaction mixture is heated at reflux for a period of about one hour. After this time the mixture is cooled, and the solid product formed is recovered by filtration. The solid is then dried to yield the desired product 5,6-dichlorobenzothiazol-2-yl isocyanate dimer.

후처리

  1. customequipped with a mechanical stirrer
  2. temperaturethermometer and reflux condenser
  3. additionAfter the addition
  4. temperaturethe reaction mixture is heated
  5. temperatureat reflux for a period of about one hour
  6. temperatureAfter this time the mixture is cooled
  7. customthe solid product formed
  8. filtrationis recovered by filtration
  9. customThe solid is then dried

출처 및 근거

ORD 기록
ord-cf319445fd2f40a1a0d34fcbc553affc
출처 데이터셋
uspto-grants-1978_04
특허 번호
US04086241

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