2-Bromo-5-fluorophenol → 1-Bromo-4-fluoro-2-[(prop-2-yn-1-yl)oxy]benzene

반응식

F[C:2]1([O:9][C:10]#[C:11][CH3:12])[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][CH2:3]1.[Br:13]C1C=CC(F)=CC=1O>>[Br:13][C:3]1[CH:4]=[CH:5][C:6]([F:8])=[CH:7][C:2]=1[O:9][CH2:10][C:11]#[CH:12]

참가 물질

반응물 2

HCID 27246002-Bromo-5-fluorophenol

HCID 670477642,4-Difluoro-2-propynyloxybenzene

생성물 1

HCID 224828471-Bromo-4-fluoro-2-[(prop-2-yn-1-yl)oxy]benzene수율 87%

실험 절차

This compound was prepared analogously to 2,4-difluoro-2-prop-ynyloxy-benzene but using 2-bromo-5-fluorphenol (15 g, 78 mmol) to give 1-bromo-4-fluoro-2-prop-2-ynyloxy-benzene 15.6 g (87%)

출처 및 근거

ORD 기록: ord-9cf435eff3634867b69798002cf033de
출처 데이터셋: uspto-grants-2004_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06716850B2

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