2-Bromo-4-fluorophenol → 2-Bromo-4-fluoro-1-prop-2-ynyloxybenzene

반응식

F[C:2]1(OC#CC)[CH:7]=C(F)C=C[CH2:3]1.[Br:13][C:14]1[CH:19]=[C:18]([F:20])[CH:17]=[CH:16][C:15]=1[OH:21]>>[Br:13][C:14]1[CH:19]=[C:18]([F:20])[CH:17]=[CH:16][C:15]=1[O:21][CH2:7][C:2]#[CH:3]

참가 물질

반응물 2

HCID 6054722-Bromo-4-fluorophenol

HCID 670477642,4-Difluoro-2-propynyloxybenzene

생성물 1

HCID 224828682-Bromo-4-fluoro-1-prop-2-ynyloxybenzene

실험 절차

This compound was prepared analogously to 2,4-difluoro-2-prop-ynyloxy-benzene but using 2-bromo-4-fluoro-phenol (15 g, 78 mmol) to give 2-bromo-4-fluoro-1-prop-2-ynyloxy-benzene 15. g (84%).

출처 및 근거

ORD 기록: ord-eaf769f452654f989afcf259cc3b535a
출처 데이터셋: uspto-grants-2004_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06716850B2

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