3-{1-[4-(4-benzyloxyphenyl)butyl]-1H-imidazol-2-yl}-1,2-propanediol → 3-{1-[4-(4-hydroxyphenyl)butyl]-1H-imidazol-2-yl)-1,2-propanediol
반응식
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][CH2:17][CH2:18][N:19]2[CH:23]=[CH:22][N:21]=[C:20]2[CH2:24][CH:25]([OH:28])[CH2:26][OH:27])=[CH:11][CH:10]=1)C1C=CC=CC=1>[C].[Pd]>[OH:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][CH2:17][CH2:18][N:19]2[CH:23]=[CH:22][N:21]=[C:20]2[CH2:24][CH:25]([OH:28])[CH2:26][OH:27])=[CH:11][CH:10]=1참가 물질
3
실험 절차
Using 3-{1-[4-(4-benzyloxyphenyl)butyl]-1H-imidazol-2-yl}-1,2-propanediol (1.22 g) and 10% palladium carbon (0.18 g), the same reaction as Reference Example 11-(v) was carried out to yield the titled compound (0.918 g) as colorless crystals.
후처리
- customthe same reaction as Reference Example 11-(v)
출처 및 근거
- ORD 기록
- ord-b40fbed80b3c44e38dc40df602416872
- 출처 데이터셋
- uspto-grants-2004_04
- 특허 번호
- US06716863B2
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