3-(1-[3-(3-Benzyloxyphenyl)propyl]-1h-imidazol-2-yl)-1,2-propanediol → 3-{1-[3-(3-hydroxyphenyl)propyl]-1H-imidazol-2-yl)-1,2-propanediol

HRID 2084387노트

반응식

HRID 2084387 반응식
C([O:8][C:9]1[CH:10]=[C:11]([CH2:15][CH2:16][CH2:17][N:18]2[CH:22]=[CH:21][N:20]=[C:19]2[CH2:23][CH:24]([OH:27])[CH2:25][OH:26])[CH:12]=[CH:13][CH:14]=1)C1C=CC=CC=1>[C].[Pd]>[OH:8][C:9]1[CH:10]=[C:11]([CH2:15][CH2:16][CH2:17][N:18]2[CH:22]=[CH:21][N:20]=[C:19]2[CH2:23][CH:24]([OH:27])[CH2:25][OH:26])[CH:12]=[CH:13][CH:14]=1

참가 물질

3

반응물 1

HCID 227333533-(1-[3-(3-Benzyloxyphenyl)propyl]-1h-imidazol-2-yl)-1,2-propanediol

생성물 1

HCID 227333623-{1-[3-(3-hydroxyphenyl)propyl]-1H-imidazol-2-yl)-1,2-propanediol수율 99.9%

시약·촉매·용매 1

HCID 178418390HCID 178418390, 화합물촉매

실험 절차

Using 3-(1-[3-(3-benzyloxyphenyl)propyl]-1H-imidazol-2-yl}-1,2-propanediol (1.30 g) and 10% palladium carbon (0.195 g), the same reaction as Reference Example 11-(v) was carried out to yield the titled compound (0.979 g) as a colorless oily substance.

후처리

  1. customthe same reaction as Reference Example 11-(v)

출처 및 근거

ORD 기록
ord-f866bbd056944567bf3d9bd323ccb473
출처 데이터셋
uspto-grants-2004_04
특허 번호
US06716863B2

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