Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
trans-2-Phenylcyclopropyl isocyanate → 4-{2-[4-amino-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl]ethyl}-N-[(1R*,2S*)-2-phenylcyclopropyl]piperidine-1-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | trans-2-Phenylcyclopropyl isocyanate | HCID 255285 | — |
| 반응물 | 2-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine | HCID 12972962 | — |
| 생성물 | 4-{2-[4-amino-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl]ethyl}-N-[(1R*,2S*)-2-phenylcyclopropyl]piperidine-1-carboxamide | HCID 20575808 | — |
반응 단계
Using the method of Examples 54-65, trans-2-phenylcyclopropyl isocyanate was reacted with 2-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The observed accurate mass was 491.3139.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06716988B2 |
| 출처 데이터셋 | uspto-grants-2004_04 |
| ORD ID | ord-95979c23ac9b4926a31b4c689ec73c04 |
| 출처 메모 | uspto-grants-2004_04 |