Ethyl 4-benzyloxy-1-(2-methylpropyl)indole-2-carboxylate → Ethyl 4-hydroxy-1-(2-methylpropyl)indole-2-carboxylate

HRID 2085126노트

반응식

HRID 2085126 반응식
C([O:8][C:9]1[CH:17]=[CH:16][CH:15]=[C:14]2[C:10]=1[CH:11]=[C:12]([C:22]([O:24][CH2:25][CH3:26])=[O:23])[N:13]2[CH2:18][CH:19]([CH3:21])[CH3:20])C1C=CC=CC=1>[C].[Pd]>[OH:8][C:9]1[CH:17]=[CH:16][CH:15]=[C:14]2[C:10]=1[CH:11]=[C:12]([C:22]([O:24][CH2:25][CH3:26])=[O:23])[N:13]2[CH2:18][CH:19]([CH3:21])[CH3:20]

참가 물질

3

반응물 1

HCID 22729270Ethyl 4-benzyloxy-1-(2-methylpropyl)indole-2-carboxylate

생성물 1

HCID 22728995Ethyl 4-hydroxy-1-(2-methylpropyl)indole-2-carboxylate

시약·촉매·용매 1

HCID 178418390HCID 178418390, 화합물촉매

실험 절차

By the reactions in the same manner as in Starting Material Synthesis Example 10 using ethyl 4-benzyloxy-1-(2-methylpropyl)indole-2-carboxylate (6.0 g) and 10% palladium-carbon (0.6 g), the title compound was obtained as pale-brown crystals.

출처 및 근거

ORD 기록
ord-2b62c205c414487fbb4321445e9c80b6
출처 데이터셋
uspto-grants-2004_04
특허 번호
US06720320B2

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