Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl Ether → 1-(2-Bromo-phenyl)-heptan-1-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl Ether | HCID 3283 | — |
| 반응물 | Tetrahydrofuran | HCID 8028 | — |
| 반응물 | 2-Bromobenzaldehyde | HCID 81129 | — |
| 반응물 | HCID 178444609 | HCID 178444609 | — |
| 용매 | Hexane | HCID 8058 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 1-(2-Bromo-phenyl)-heptan-1-ol | HCID 22731273 | — |
반응 단계
Following General Procedure K and using 2-bromo-benzaldehyde (1.5 g, 8 mmol), 15 mL of anhydrous tetrahydrofuran, and a 2M solution of n-hexyl magnesium bromide solution in ether (6 mL, 12 mmol) followed by flash column chromatography using 10% ethyl acetate in hexane, the title compound was obtained (1.86 g, 85%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06720423B2 |
| 출처 데이터셋 | uspto-grants-2004_04 |
| ORD ID | ord-393e82db8a8c4988ba6d5b36ac145e2c |
| 출처 메모 | uspto-grants-2004_04 |