Cyclohexane, (ethenyloxy)- → HCID 12994198, 화합물

HRID 2085625노트

반응식

HRID 2085625 반응식
C1(C)C=CC(S([O-])(=O)=O)=CC=1.[NH+]1C=CC=CC=1.[C:18]([O:23][CH2:24][CH:25]([CH3:27])[CH3:26])(=[O:22])[C@@H:19]([CH3:21])[OH:20].[CH:28]([O:30][CH:31]1[CH2:36][CH2:35][CH2:34][CH2:33][CH2:32]1)=[CH2:29]>C(OCC)(=O)C>[CH:31]1([O:30][CH:28]([O:20][C@H:19]([CH3:21])[C:18]([O:23][CH2:24][CH:25]([CH3:27])[CH3:26])=[O:22])[CH3:29])[CH2:36][CH2:35][CH2:34][CH2:33][CH2:32]1

참가 물질

5

반응물 3

HCID 75129Cyclohexane, (ethenyloxy)-HCID 466102Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1)HCID 104869892-Methylpropyl-(R)-2-hydroxypropanoate

생성물 1

HCID 12994198HCID 12994198, 화합물수율 99.5%

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

A catalytic amount of pyridinium para-toluenesulfonate was added to 29.2 g (0.2 mole) of isobutyl (R)-(+)-lactate and 28.0 g (0.22 mole) of cyclohexyl vinyl ether. The resulting mixture was stirred at room temperature for 4 hours to give rise to a reaction. Thereto was added 100 ml of ethyl acetate, followed by washing with 100 ml of a saturated aqueous sodium hydrogen carbonate solution, 40 ml of water and 40 ml of a saturated aqueous sodium chloride solution in this order. The washed material was dried over anhydrous sodium sulfate and then subjected to vacuum distillation to remove the solvent, whereby was obtained 54.2 g (yield: 99.4%) of an oily title compound (diastereomixture).

후처리

  1. customto give rise
  2. customto a reaction
  3. washby washing with 100 ml of a saturated aqueous sodium hydrogen carbonate solution, 40 ml of water and 40 ml of a saturated aqueous sodium chloride solution in this order
  4. dry with materialThe washed material was dried over anhydrous sodium sulfate
  5. distillationsubjected to vacuum distillation
  6. customto remove the solvent

출처 및 근거

ORD 기록
ord-f3ffd66015e743289eaaf4ea9e62d370
출처 데이터셋
uspto-grants-2004_04
특허 번호
US06720463B1

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