Triethylamine → Trans-3-(naphth-2-yl)-acrylic acid-N-(2-carboxy-4-fluoro-phenyl)-amide
반응식
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1/[CH:11]=[CH:12]/[C:13](Cl)=[O:14].[NH2:16][C:17]1[CH:25]=[CH:24][C:23]([F:26])=[CH:22][C:18]=1[C:19]([OH:21])=[O:20].C(N(CC)CC)C>O1CCCC1>[C:19]([C:18]1[CH:22]=[C:23]([F:26])[CH:24]=[CH:25][C:17]=1[NH:16][C:13](=[O:14])/[CH:12]=[CH:11]/[C:2]1[CH:3]=[CH:4][C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH:1]=1)([OH:21])=[O:20]참가 물질
5
실험 절차
Prepared analogously to Example 31 from trans-3-(naphth-2-yl)-acrylic acid chloride and 2-amino-5-fluoro-benzoic acid in tetrahydrofuran with the addition of triethylamine.
출처 및 근거
- ORD 기록
- ord-a7ffaa6976574e37bfeece789e91bf77
- 출처 데이터셋
- uspto-grants-2004_04
- 특허 번호
- US06727250B2
반응 노트
불러오는 중…