HCID 22313821, 화합물 → HCID 22316690, 화합물

HRID 2086694노트

반응식

HRID 2086694 반응식
Cl.[F:2][C:3]1[CH:8]=[C:7]([S:9](=[O:12])(=[O:11])[NH2:10])[CH:6]=[CH:5][C:4]=1[NH:13][NH2:14].[F:15][C:16]([F:35])([F:34])[C:17](=O)[CH2:18][C:19]([C:21]1[CH:26]=[CH:25][C:24]([C:27]2[N:28]=[CH:29][S:30][CH:31]=2)=[C:23]([CH3:32])[CH:22]=1)=O>>[F:2][C:3]1[CH:8]=[C:7]([S:9]([NH2:10])(=[O:12])=[O:11])[CH:6]=[CH:5][C:4]=1[N:13]1[C:19]([C:21]2[CH:26]=[CH:25][C:24]([C:27]3[N:28]=[CH:29][S:30][CH:31]=3)=[C:23]([CH3:32])[CH:22]=2)=[CH:18][C:17]([C:16]([F:35])([F:34])[F:15])=[N:14]1

참가 물질

3

반응물 2

HCID 22313821HCID 22313821, 화합물HCID 22316599HCID 22316599, 화합물

생성물 1

HCID 22316690HCID 22316690, 화합물

실험 절차

The title compound was prepared according to the procedure of Example 60 using 2-fluoro-4-sulfamoylphenylhydrazine hydrochloride instead of 3-fluoro-4-(methylsulfonyl)phenylhydrazine hydrochloride and 4,4,4-trifluoro-1-[3-methyl-4-(4-thiazolyl)phenyl]butane-1,3-dione instead of 4,4,4-trifluoro-1-[4-(2-furyl)phenyl]butane-1,3-dione in step 2.

출처 및 근거

ORD 기록
ord-eb5256b69db7484c9316fe6c8d7fa0a0
출처 데이터셋
uspto-grants-2004_04
특허 번호
US06727238B2

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