1-(2-Phenyl-1,3-thiazol-4-yl)ethan-1-one → 2-Methyl-N-(3-{1-[1-(2-phenyl-1,3-thiazol-4-YL)ethyl]-4-piperidinyl}phenyl)propanamide

HRID 2087344노트

반응식

HRID 2087344 반응식
[C:1]1([C:7]2[S:8][CH:9]=[C:10]([C:12](=O)[CH3:13])[N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:15][CH:16]([CH3:32])[C:17]([NH:19][C:20]1[CH:25]=[CH:24][CH:23]=[C:22]([CH:26]2[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]2)[CH:21]=1)=[O:18]>>[CH3:15][CH:16]([CH3:32])[C:17]([NH:19][C:20]1[CH:25]=[CH:24][CH:23]=[C:22]([CH:26]2[CH2:31][CH2:30][N:29]([CH:12]([C:10]3[N:11]=[C:7]([C:1]4[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=4)[S:8][CH:9]=3)[CH3:13])[CH2:28][CH2:27]2)[CH:21]=1)=[O:18]

참가 물질

3

반응물 2

HCID 6048191-(2-Phenyl-1,3-thiazol-4-yl)ethan-1-oneHCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamide

생성물 1

HCID 220491162-Methyl-N-(3-{1-[1-(2-phenyl-1,3-thiazol-4-YL)ethyl]-4-piperidinyl}phenyl)propanamide

실험 절차

Prepared by Procedure F and Scheme R using 1-(2-phenyl-1,3-thiazol-4-yl)ethanone and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 434.2 (M+H)+.

후처리

  1. customPrepared by Procedure F and Scheme R

출처 및 근거

ORD 기록
ord-82bc24e8e88d4e3dadd081ade8e0a756
출처 데이터셋
uspto-grants-2004_04
특허 번호
US06727264B1

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