2,3-Dihydro-1,4-benzodioxin-6-carbaldehyde → N-{3-[1-(2,3-Dihydro-1,4-benzodioxin-6-ylmethyl)-4-piperidinyl]phenyl}-2-methylpropanamide

HRID 2087365

반응식

HRID 2087365 반응식
[O:1]1[C:6]2[CH:7]=[CH:8][C:9]([CH:11]=O)=[CH:10][C:5]=2[O:4][CH2:3][CH2:2]1.[CH3:13][CH:14]([CH3:30])[C:15]([NH:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH:24]2[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]2)[CH:19]=1)=[O:16]>>[O:1]1[C:6]2[CH:7]=[CH:8][C:9]([CH2:11][N:27]3[CH2:28][CH2:29][CH:24]([C:20]4[CH:19]=[C:18]([NH:17][C:15](=[O:16])[CH:14]([CH3:13])[CH3:30])[CH:23]=[CH:22][CH:21]=4)[CH2:25][CH2:26]3)=[CH:10][C:5]=2[O:4][CH2:3][CH2:2]1

참가 물질

3

반응물 2

HCID 2481272,3-Dihydro-1,4-benzodioxin-6-carbaldehydeHCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamide

생성물 1

HCID 22049436N-{3-[1-(2,3-Dihydro-1,4-benzodioxin-6-ylmethyl)-4-piperidinyl]phenyl}-2-methylpropanamide

실험 절차

Prepared by Procedure F and Scheme R using 2,3-dihydro-1,4-benzodioxine-6-carbaldehyde and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 395.1 (M+H)+.

후처리

  1. customPrepared by Procedure F and Scheme R

출처 및 근거

ORD 기록
ord-08fb81aef2ac4622bff45cf273edb485
출처 데이터셋
uspto-grants-2004_04
특허 번호
US06727264B1

연결된 노트

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