Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Bromophenacyl bromide → N-[4-(4-Bromo-phenyl)-1H-imidazol-2-yl]-acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Bromophenacyl bromide | HCID 7454 | — |
| 반응물 | HCID 178475102 | HCID 178475102 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | N-[4-(4-Bromo-phenyl)-1H-imidazol-2-yl]-acetamide | HCID 10468856 | — |
반응 단계
A mixture of 2-bromo-1-(4-bromophenyl)ethanone (2.00 g, 7.20 mmol) and acetylguanidine (2.18 g, 21.6 mmol) in DMF (40 mL) was stirred at rt for 48 h. The solution was concentrated to dryness in vacuo and the resulting brown solid was of sufficient purity for use in the next step. LCMS: Anal. Calcd. for C11H10BrN3O: 279, 281; found: 280, 282 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07745636B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-9095334553934822abb0be22ce7699c7 |
| 출처 메모 | uspto-grants-2010_06 |