Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(tert-Butyldimethylsilyloxy)cyclohexanone → N-{1-[4-(tert-Butyl-dimethyl-silanyloxy)-cyclohexyl]-azetidin-3-yl}-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(tert-Butyldimethylsilyloxy)cyclohexanone | HCID 10609430 | — |
| 반응물 | N-Azetidin-3-yl-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamide TFA salt | HCID 86660176 | — |
| 생성물 | N-{1-[4-(tert-Butyl-dimethyl-silanyloxy)-cyclohexyl]-azetidin-3-yl}-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamide | HCID 58548829 | — |
반응 단계
The title compound was prepared as a white solid from reaction of (N-azetidin-3-yl-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamide TFA salt (as prepared in Example 1, Step D) and 4-(tert-butyl-dimethyl-silanyloxy)-cyclohexanone using the procedure described in Step E of Example 1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08436023B2 |
| 출처 데이터셋 | uspto-grants-2013_05 |
| ORD ID | ord-dd5ad6d98f844a1eb99a60ee5647a9ca |
| 출처 메모 | uspto-grants-2013_05 |