Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Oxocyclohexane-1-carbonitrile → N-[1-(4-Cyano-cyclohexyl)-azetidin-3-yl]-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Oxocyclohexane-1-carbonitrile | HCID 12235639 | — |
| 반응물 | N-Azetidin-3-yl-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamide TFA salt | HCID 86660176 | — |
| 생성물 | N-[1-(4-Cyano-cyclohexyl)-azetidin-3-yl]-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamide | HCID 54756152 | — |
반응 단계
The title compound was prepared as a white solid from reaction of (N-Azetidin-3-yl-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamide TFA salt (as prepared in Example 1, Step D) and 4-cyano-cyclohexanone using the procedure described in Step E of Example 1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08436023B2 |
| 출처 데이터셋 | uspto-grants-2013_05 |
| ORD ID | ord-074db556be4c472781f63884bf813fa4 |
| 출처 메모 | uspto-grants-2013_05 |