HCID 58548846, 화합물 → HCID 54754848, 화합물

HRID 2089180노트

반응식

HRID 2089180 반응식
[NH:1]1[CH2:4][CH:3]([NH:5][C:6](=[O:22])[CH2:7][NH:8][C:9]2[C:17]3[C:12](=[CH:13][CH:14]=[C:15]([C:18]([F:21])([F:20])[F:19])[CH:16]=3)[NH:11][N:10]=2)[CH2:2]1.[OH:23][C:24]1([C:31]2[S:35][CH:34]=[N:33][CH:32]=2)[CH2:29][CH2:28][C:27](=O)[CH2:26][CH2:25]1>>[OH:23][C:24]1([C:31]2[S:35][CH:34]=[N:33][CH:32]=2)[CH2:25][CH2:26][CH:27]([N:1]2[CH2:2][CH:3]([NH:5][C:6](=[O:22])[CH2:7][NH:8][C:9]3[C:17]4[C:12](=[CH:13][CH:14]=[C:15]([C:18]([F:20])([F:19])[F:21])[CH:16]=4)[NH:11][N:10]=3)[CH2:4]2)[CH2:28][CH2:29]1

참가 물질

3

반응물 2

HCID 58548846HCID 58548846, 화합물HCID 590174394-Hydroxy-4-(thiazol-5-yl)cyclohexanone

생성물 1

HCID 54754848HCID 54754848, 화합물

실험 절차

The title compound was prepared as a white solid from reaction of N-azetidin-3-yl-2-(5-trifluoromethyl-1H-indazol-3-ylamino)-acetamide (as prepared in Example 41, Step A) and 4-hydroxy-4-thiazol-5-yl-cyclohexanone using the procedure described in Step E of Example 1.

출처 및 근거

ORD 기록
ord-aa6c69be84eb4453aa24f77bae1ed0a1
출처 데이터셋
uspto-grants-2013_05
특허 번호
US08436023B2

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