Morpholine → 5-Chloro-3-(morpholin-4-yl)methyl-7-nitro-2-phenyl-1H-indole

HRID 2089568노트

반응식

HRID 2089568 반응식
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[C:9]([N+:11]([O-:13])=[O:12])[CH:10]=1)[NH:7][C:6]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[C:5]2[CH:20]=O.[NH:22]1[CH2:27][CH2:26][O:25][CH2:24][CH2:23]1>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[C:9]([N+:11]([O-:13])=[O:12])[CH:10]=1)[NH:7][C:6]([C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)=[C:5]2[CH2:20][N:22]1[CH2:27][CH2:26][O:25][CH2:24][CH2:23]1

참가 물질

3

반응물 2

HCID 8083MorpholineHCID 866438345-Chloro-3-formyl-7-nitro-2-phenyl-1H-indole

생성물 1

HCID 684776515-Chloro-3-(morpholin-4-yl)methyl-7-nitro-2-phenyl-1H-indole

실험 절차

5-Chloro-3-formyl-7-nitro-2-phenyl-1H-indole prepared in Step A of Preparation 43 and morpholine were reacted according to the same procedure as Step B of Preparation 43 to give the title compound.

후처리

  1. customwere reacted
  2. customaccording to the same procedure as Step B of Preparation 43

출처 및 근거

ORD 기록
ord-23b0ecb5fd824bc9b431741b26670037
출처 데이터셋
uspto-grants-2013_05
특허 번호
US08436038B2

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