Ammonium Chloride → 4-(5-Chloro-2-phenyl-1H-indol-7-yl)amino-cyclohexane-1-carboxylic acid amide

반응식

[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[C:9]([NH:11][CH:12]3[CH2:17][CH2:16][CH:15]([C:18]([OH:20])=O)[CH2:14][CH2:13]3)[CH:10]=1)[NH:7][C:6]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[CH:5]2.[NH4+:27].[Cl-]>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[C:9]([NH:11][CH:12]3[CH2:17][CH2:16][CH:15]([C:18]([NH2:27])=[O:20])[CH2:14][CH2:13]3)[CH:10]=1)[NH:7][C:6]([C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1)=[CH:5]2

참가 물질

반응물 2

HCID 25517Ammonium Chloride

HCID 68476533HCID 68476533, 화합물

생성물 1

HCID 684787454-(5-Chloro-2-phenyl-1H-indol-7-yl)amino-cyclohexane-1-carboxylic acid amide

실험 절차

4-(5-Chloro-2-phenyl-1H-indol-7-yl)amino-cyclohexane-1-carboxylic acid prepared in Example 102 and NH4Cl were reacted according to the same procedure as Example 92 to give the title compound.

출처 및 근거

ORD 기록: ord-2dfac61340d34de3a8be3a15bfb7df69
출처 데이터셋: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08436038B2

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