Methyl triflate → 1-Methyl-3-(piperidine-1-sulfonyl)-3h-imidazol-1-ium triflate salt
반응식
[N:1]1([S:6]([N:9]2[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]2)(=[O:8])=[O:7])[CH:5]=[CH:4][N:3]=[CH:2]1.[O:15](C)[S:16]([C:19]([F:22])([F:21])[F:20])(=[O:18])=[O:17]>C(Cl)Cl>[O-:18][S:16]([C:19]([F:22])([F:21])[F:20])(=[O:17])=[O:15].[CH3:19][N+:3]1[CH:4]=[CH:5][N:1]([S:6]([N:9]2[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]2)(=[O:8])=[O:7])[CH:2]=1참가 물질
4
실험 절차
To a solution of compound 1-H (79.6 mg, 0.37 mmol) in CH2Cl2 (2 mL), cooled to 0° C., was added methyl triflate (46 μL, 0.407 mmol). The reaction mixture was allowed to warm to ambient temperature and stirred for 3 hours. The solvent was evaporated under reduced pressure to afford compound 1-I as a white solid. MS (method 2): m/z 229.9 (MH+).