Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Toluene → 3-(4-Chlorocinnamoyl)-propionic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Toluene | HCID 1140 | — |
| 반응물 | 4-Chlorobenzaldehyde | HCID 7726 | — |
| 반응물 | Piperidine | HCID 8082 | — |
| 반응물 | Levulinic Acid | HCID 11579 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-(4-Chlorocinnamoyl)-propionic acid | HCID 54351013 | 44% |
반응 단계
To a dry 250 ml flask equipped with a magnetic stirrer, Dean-Stark trap, and reflux condenser was charged 15 g of 4-chlorobenzaldehyde, 12.4 g levulenic acid, 5.7 ml of piperidine, and 100 ml of toluene. The reaction was refluxed for 3 hours, after which no water was observed to azeotrope from the solution. The reaction was cooled and stripped to yield a reddish-brown liquid which was triturated with hexane to yield 11.2 g of product as a yellow solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05728694 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-a02c0eb3e0774586ad570d8875582725 |
| 출처 메모 | uspto-grants-1998_03 |