N-Methylethylamine → HCID 59563516, 화합물

반응식

[NH2:1][C:2]1[C:11]2[N:12]=[C:13]([CH2:35][CH2:36][CH2:37][CH3:38])[N:14]([CH2:15][CH2:16][CH2:17][N:18]([CH2:23][C:24]3[CH:25]=[C:26]([CH2:30][C:31]([O:33][CH3:34])=[O:32])[CH:27]=[CH:28][CH:29]=3)[CH2:19][CH2:20][CH2:21]Cl)[C:10]=2[C:9]2[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=2[N:3]=1.[CH2:39]([NH:41][CH3:42])[CH3:40]>>[NH2:1][C:2]1[C:11]2[N:12]=[C:13]([CH2:35][CH2:36][CH2:37][CH3:38])[N:14]([CH2:15][CH2:16][CH2:17][N:18]([CH2:23][C:24]3[CH:25]=[C:26]([CH2:30][C:31]([O:33][CH3:34])=[O:32])[CH:27]=[CH:28][CH:29]=3)[CH2:19][CH2:20][CH2:21][N:41]([CH2:39][CH3:40])[CH3:42])[C:10]=2[C:9]2[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=2[N:3]=1

참가 물질

반응물 2

HCID 12219N-Methylethylamine

HCID 68430884Methyl 2-(3-(((3-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl)(3-chloropropyl)amino)methyl)phenyl)acetate

생성물 1

HCID 59563516HCID 59563516, 화합물

실험 절차

The title compound was prepared by the method of example 11 step (x) using the product of example 11 step (ix) (627 mg) and N-ethylmethylamine (1 ml) as a white solid 65 mg.

출처 및 근거

ORD 기록: ord-0104eddfd58c4d50a7b6d4ef05190244
출처 데이터셋: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08436178B2

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